Dibenzocyclooctyne-maleimide, for Copper-free Click Chemistry

Code: 760668-5MG D2-231

Application

Maleimide functionalized cyclooctyne derivative for incorporation of the cyclooctyne moiety into thiol containing compounds or biomolecules. Cyclooctynes are usef...


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Your Price
€88.40 5MG
€108.73 inc. VAT

Application

Maleimide functionalized cyclooctyne derivative for incorporation of the cyclooctyne moiety into thiol containing compounds or biomolecules. Cyclooctynes are useful in strain-promoted copper-free azide-alkyne cycloaddition reactions. This dibenzocyclooctyne will react with azide functionalized compounds or biomolecules without the need for a Cu(I) catalyst to result in a stable triazole linkage. Applications Include: Protein-peptide conjugates Antibody-enzyme or antibody-drug conjugates Protein or peptide-oligonucleotide conjugates Surface modification

Packaging

1, 5, 50 mg in amber glass bottle

formsolid
InChI keyNHFQNAGPXIVKND-UHFFFAOYSA-N
InChI1S/C25H21N3O4/c29-22(14-16-27-23(30)11-12-24(27)31)26-15-13-25(32)28-17-20-7-2-1-5-18(20)9-10-19-6-3-4-8-21(19)28/h1-8,11-12H,13-17H2,(H,26,29)
Quality Level100
reaction suitabilityreaction type: click chemistry, reagent type: cross-linking reagent
SMILES stringO=C(N1CCC(NCCC(N2CC3=C(C=CC=C3)C#CC4=C2C=CC=C4)=O)=O)C=CC1=O
storage temp.−20°C
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